PAMORAs
If you have been diagnosed with opioid-induced constipation (OIC) and you have not found the relief you need with laxatives and lifestyle changes, your healthcare professional might suggest that you take a Peripherally acting mu-opioid receptor antagonist or PAMORA for short1. There are different PAMORAs available so discuss the most suitable for you with your healthcare professional.
PAMORAs are treatments specifically designed to treat OIC. PAMORAs stop your opioid binding with one type of opioid receptors in your digestive tract (these ones are called 'mu receptors', but there are several types) to relieve constipation, without affecting the opioid's ability to relieve pain.1
A PAMORA is a targeted medicine designed specifically to treat OIC without interfering with the pain relief that your opioid medication brings.1